Technology to support Patient Adherence in Clinical Trials

One of the major issues in Clinical research and analysis is adherence (or compliance) of patient's to the clinical trial protocol. This is especially an issue in evaluation of PK/PD, safety, efficacy and dose estimation. 

Currently most of the compliance issues are passively handled and patients are considered "censored" when they drop out from the study. This leads complexities in statistical interpretation and reporting. However there has been a recent surge in new technology that is aimed to measuring adherence and improving it.

Compliance process can be initiated by using direct communication methods such as telephone, email and fax etc., Another important aspect is patient education and interaction at different levels including the pharmacist. 

Currently the most advanced technology for monitoring compliance in taking the drug is use of biosensors based on RFID sensor devices that provide a disposable, inexpensive, state-of-the-art method. Another method is using drug tagging to track usage.

DIA is organizing a conference on this topic in May 2008 :http://www.diahome.org/DIAHOME/Education/FindEducationalOffering.aspx?productID=16491&eventType=Meeting